In 2025, digital health companies are driving a landscape that is more dynamic and innovative than ever before. As technology continues to advance, a new wave of startups is emerging, each bringing unique solutions to the healthcare industry.
From AI-driven platforms that streamline clinical trials to comprehensive systems that digitize medical records, these companies are not only transforming how healthcare is delivered but also enhancing patient outcomes and operational efficiency. This article highlights eight digital health companies that are leading the charge in healthcare. These startups are setting new standards for what is possible in the realm of digital health.
Meet the digital health companies shaping the future of healthcare in 2025
1. Penguin AI
Founded: 2023 | Raised: $3M | Funding Round: Pre-seed | Verticals: Enterprise & AI, Health | HQ: Palo Alto, CA
Penguin AI is one of the top digital health companies helping healthcare providers bring the power of large language models (LLMs) into real-world medical settings. Built specifically for the unique needs of healthcare, Penguin AI’s platform makes it easier and safer for teams to build, test, and deploy custom AI models. Whether it’s streamlining back-end operations or supporting more personalized patient care, Penguin AI is all about making advanced technology practical and useful for doctors, clinicians, and patients. In 2025, they will continue bridging the gap between cutting-edge AI and everyday healthcare delivery.
2. Biorce
Founded: 2024 | Raised: N/A | Funding Round: Seed | Verticals: Health | HQ: Barcelona, Spain
Clinical trials are known for being slow and expensive, but Biorce is working to change that. This digital health company is reimagining how clinical trials are run, using technology to speed up timelines and slash costs. Biorce’s platform helps teams reduce trial expenses by over 50% and cut down timelines by more than 40%, all while improving accuracy and reducing the risk of human error. By streamlining the process from end to end, Biorce is making drug development faster, safer, and more efficient, which is a significant step forward for medical innovation.
3. Bioptimus
Founded: 2023 | Raised: $76M | Funding Round: Series A | Verticals: Health | HQ: Paris, France
Bioptimus is building a universal AI foundation model designed to accelerate scientific discovery. By linking biology across every level — molecules, cells, tissues, and entire organisms — their platform turns complex, multiscale data into meaningful insights. It’s a game-changer for researchers looking to unlock new breakthroughs in biomedicine, biotech, and beyond. With generative AI at its core, Bioptimus is helping scientists move faster, ask better questions, and explore possibilities that were out of reach just a few years ago.
4. Honey Health, Inc.
Founded: 2023 | Raised: N/A | Funding Round: Undisclosed | Verticals: Health | HQ: Menlo Park, CA
Honey Health is rethinking how healthcare systems run behind the scenes. By introducing AI co-workers to handle repetitive admin tasks, like sorting faxes, managing prior authorizations, and aggregating data, they’re helping healthcare teams work smarter, not harder. This results in less time spent on paperwork and more time for patient care. Honey Health partners closely with providers to streamline operations, increase revenue, and keep up with growing patient demand. In a space where every minute counts, their AI-centered approach is making a real difference.
5. Fourier Health
Founded: 2023 | Raised: $2.9M | Funding Round: Seed | Verticals: Health | HQ: Miami, FL
Fourier Health is a digital health startup transforming the way healthcare providers manage patient information with their AI platform. By creating tailored clinical summaries, Fourier Health helps reduce the administrative burden on healthcare professionals, allowing them to focus more on patient care. Their platform benefits patients with extensive medical histories, offering solutions like patient intake facilitation, second opinion summaries, and pre-charting for annual wellness visits. With Fourier Health, healthcare providers can enhance their efficiency and revenue, making it a game-changer in digital health.
6. Medallion
Founded: 2020 | Raised: $85M | Funding Round: Series C | Verticals: Health, Deeptech | HQ: San Francisco, CA
Medallion is a digital health company simplifying the complex world of healthcare paperwork with its innovative licensing and credentialing platform. Designed to meet the administrative needs of the healthcare industry, Medallion's platform offers new licensing and renewal facilities, primary source verification, continuing medical education (CME) tracking, document management, and payer enrollment. By streamlining these processes, Medallion enables healthcare providers and telemedicine companies to focus less on paperwork and more on patient care, making it an invaluable asset in the digital health sector.
7. Visby Medical
Founded: 2012 | Raised: $436M | Funding Round: Series E | Verticals: Health | HQ: San Jose, CA
Visby Medical makes disease diagnosis quick, accurate, and accessible to everyone. They are developing an innovative device platform that promises to redefine how we test and treat illnesses. Currently, Visby Medical is in the FDA submission process for its first two products, a sexual health test and a COVID-19 test, with expectations for market clearance later this year. As they continue to operate in stealth mode, Visby Medical remains a promising force in the digital health landscape, driven by its commitment to improving healthcare accessibility and accuracy.
We're proud to call Visby Medical one of our unicorns at Plug and Play. To learn more about their incredible journey and impact, watch this video on their life-changing experience and partnership with us.
8. Helium Health
Founded: 2016 | Raised: $63M | Funding Round: Series B | Verticals: Health, Fintech, Insurtech | HQ: Lagos, Nigeria
Helium Health is a digital health startup transforming the healthcare landscape in Africa by digitizing medical records and streamlining operations for hospitals and clinics. With a comprehensive suite of software tools, Helium Health not only helps healthcare providers manage their operations more efficiently but also offers telemedicine solutions to connect doctors with patients. Their mission is to build a modern and affordable healthcare system, aiming to become the largest healthcare data exchange in Africa. Helium Health's innovative approach to healthcare digitization positions it as a pivotal player in improving healthcare accessibility and quality across the continent.
9. Charta Health
Founded: 2023 | Raised: $30M | Funding Round: Series A | Verticals: Health | HQ: San Francisco, CA
Charta Health is transforming the medical billing landscape with its AI-powered platform designed to optimize billing and coding workflows. By conducting a pre-bill review of each chart, Charta Health identifies missed coding opportunities, prevents claim denials, and ensures adherence to billing standards. This innovative approach not only enhances efficiency but also maximizes revenue for healthcare providers, making Charta Health a key player in the digital health sector.
10. Neura Health
Founded: 2020 | Raised: $10M | Funding Round: Seed | Verticals: Health | HQ: New York, NY
Neura Health has many useful virtual features designed to provide faster access to neurologists, such as a condition tracker, weekly care coaching sessions, and 24/7 care team access. However, if a brain scan is needed, they refer to a physical location for that service. Furthermore, Neura Health is expanding its capacity for brick-and-mortar practices by helping it extend its services outside its typical geographical reach and office hours. This presents an innovative way for hospitals to delight patients and grow revenue by leveraging Neura’s neurology network as a virtual-first layer (bandwidth extenders for the neurology department).
